Dr. Adam Moeser is an associate professor and the Matilda R. Wilson Endowed Research Chair for the Department of Large Animal Clinical Sciences and director of the Gastrointestinal Stress Biology Laboratory at Michigan State University. Centered at the intersection of human and animal health, the focus of Moeser’s research program is understanding how early-life adversity (e.g. adverse childhood events (ACE’s), psychosocial trauma, etc.) influences the development of brain-gut axis communication and increased disease risk across the lifespan. Current areas of research focus include interactions between ELA and biological sex on development of GI neuroimmune interactions and disease risk throughout the lifespan, origins of sex differences in mast cells and mast cell-mediated diseases, epigenetic and transcriptional programming of mast cells by ELA, and role of mast cells in brain-gut axis communication.
Publications
2023, Negative Antigenuria in a Dog with Suspected Central Nervous System Localized Blastomycosis
- Published in Journal of the American Animal Hospital Association, impact factor 1.41
2022, Anticonvulsants
2022, Early life adversity programs a hyperactive mast cell phenotype and induces long-lasting changes in the mast cell transcriptome
- Published in The Journal of Immunology, impact factor 5.43
2022, Androgen Receptor Deficiency Eliminates Sex Differences in Mast Cells
- Published in The Journal of Immunology, impact factor 5.43
2022, Mast cell–derived factor XIIIA contributes to sexual dimorphic defense against group B streptococcal infections
- Published in the Journal of Clinical Investigation, 15.9
2022, Sex Differences in Mast Cell–Associated Disorders: A Life Span Perspective
- Published in Cold Spring Harbor Perspectives in Biology, impact factor 9.708
2022, Transition milk stimulates intestinal development of neonatal Holstein calves
- Published in Journal of Dairy Science, impact factor 4.225
2022, Biological sex: an understudied factor driving disease susceptibility in pigs
- Published in Journal of Animal Science
2022, Effects of a multi-strain Bacillus subtilis -based direct-fed microbial on immunity markers and intestinal morphology in diets fed to weanling pigs
- Published in Transitional Animal Science, impact factor 0.507
2022, Early life adversity drives sex-specific anhedonia and meningeal immune gene expression through mast cell activation
- Published in Brain, Behavior, and Immunity, impact factor 19.227
2022, Future of biomedical, agricultural, and biological systems research using domesticated animals
- Published in Biology of Reproduction, impact factor 4.161
2022, Impaired KDM2B-mediated PRC1 recruitment to chromatin causes defective neural stem cell self-renewal and ASD/ID-like behaviors
- Published in iScience, impact factor 5.08
2022, Developmental alterations of intestinal SGLT1 and GLUT2 induced by early weaning coincides with persistent low-grade metabolic inflammation in female pigs
- Published in American Journal of Physiology - Gastrointestinal and Liver Physiology, impact factor 4.877
